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Caroline Whitbeck Elmer G. Beamer-Hubert H. Schneider Emerita Professor in Ethics Case Western Reserve University Case Western Reserve University More Posts
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When the Proposed Research May be Objectionable to the Source of the Tissue
Secondary Title When the Proposed Research May be Objectionable to the Source of the Tissue


Author(s) Thomas H. Murray

A scenario meant to stimulate discussion about the ethical issues that arise in genetic research and ethnic group susceptibility.

Author(s): Thomas H. Murray, Ph.D.

A researcher interested in the genetics of alcoholism has identified what she believes is a candidate gene for susceptibility. Knowing the prevalence of alcoholism is especially high in certain ethnic groups, she asks a tissue repository for samples of tissue from Native Americans living in the Southwest, and from a control group of non-Native Americans from the same region. She neither requests nor needs any identifying information with each sample other than whether it is from a Native American, so that the samples could be taken from unlinked samples.

  • Is it likely that at least some people whose specimens might be used in this study might object to it? If so, what objections might they offer?
  • What arguments might the scientist proposing the study give in favor of obtaining the samples even if some of the sample sources might object if they knew the use to which it was being put?
  • Should institutions or funders of research require that potentially objectionable research be subject to special review? How might such a review be conducted, and by whom?
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Contributor(s) Caroline Whitbeck
Notes Caroline Whitbeck introduced methods and modules for discussing numerous issues in responsible conduct of research at a Sigma Xi Forum in 2000. Partial funding for the development of this material came from an NIH grant. You can find the entire sequence on the OEC at Some information in these historical modules may be out-of-date; for instance, there may be a new edition of the professional society’s code that is referred to in an item. If you have suggestions for updates, please contact the OEC.
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Year 2000
Publisher National Academy of Engineering, Online Ethics Center
Language English
  • Using Case Studies Bibliography


    This bibliography includes examples of different ways instructors have used case studies to introduce ethical topics to their students and resources for finding cases and incorporating them into the classroom.

    Author(s) Kelly Laas
    Year 2016
  • Added08/23/2006

    In this essay, Dr. Whitbeck outlines an 'agent-centered' approach to learning ethics. The central aim is to prepare students to act wisely and responsibly when faced with moral problems. She provides a number of examples and cases with descriptions of questions and directions for promoting student participation and stimulating thought and discussion.

    Year 1995
Cite this page: "When the Proposed Research May be Objectionable to the Source of the Tissue" Online Ethics Center for Engineering 9/11/2006 OEC Accessed: Tuesday, October 25, 2016 <>